{"id":25,"date":"2026-04-10T18:08:51","date_gmt":"2026-04-10T16:08:51","guid":{"rendered":"https:\/\/reaclongevity.com\/?page_id=25"},"modified":"2026-10-21T16:45:23","modified_gmt":"2026-10-21T14:45:23","slug":"protocolli","status":"publish","type":"page","link":"https:\/\/reaclongevity.com\/en\/protocolli\/","title":{"rendered":"Protocols"},"content":{"rendered":"<main id='bde-main'><section class=\"bde-f-container-25-343 bde-f-container ribz-section ribz-section--hero\" aria-labelledby=\"pc-title\"><div class=\"bde-f-container-25-342 bde-f-container ribz-wrap ribz-wrap--hero ribz-split ribz-split--center ribz-split--media\"><div class=\"bde-f-container-25-339 bde-f-container\"><p class=\"bde-f-text-25-333 bde-f-text ribz-eyebrow ribz-eyebrow--light ribz-eyebrow--rule\">\nThe Inside Blue Zone pathway\n<\/p><h1 class=\"bde-f-text-25-334 bde-f-text ribz-h1\" id=\"pc-title\">\nA pathway to take care of your longevity\n<\/h1><p class=\"bde-f-text-25-335 bde-f-text ribz-lead ribz-lead--hero\">\nThree areas, a defined sequence and a doctor who follows you from start to finish: this is how the pathway you can start at a Longevity Center in the network works.\n<\/p><div class=\"bde-f-container-25-338 bde-f-container ribz-actions ribz-pc-actions\"><a class=\"bde-f-text-link-25-336 bde-f-text-link ribz-btn ribz-btn--aqua\" href=\"https:\/\/reaclongevity.com\/en\/longevity-center\/#trova-centro\" target=\"_self\">\nFind a centre \u2192\n<\/a><a class=\"bde-f-text-link-25-337 bde-f-text-link ribz-btn ribz-btn--line\" href=\"#come-si-svolge\" target=\"_self\">\nWhat happens during a session\n<\/a><\/div><\/div><figure class=\"bde-f-container-25-341 bde-f-container ribz-pc-hero-figure\"><img loading=\"lazy\" decoding=\"async\" class=\"bde-f-image-25-340 bde-f-image ribz-pc-hero-img\" src=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/04\/Pazienti-REAC-Longevity-IBZ-1536x864.webp\" alt=\"Two people smiling outdoors\" width=\"768\" height=\"432\"><\/figure><\/div><\/section><section class=\"bde-f-container-25-369 bde-f-container ribz-section ribz-section--alt\" aria-labelledby=\"pc-aree-title\"><div class=\"bde-f-container-25-368 bde-f-container ribz-wrap\"><div class=\"bde-f-container-25-347 bde-f-container ribz-intro\"><p class=\"bde-f-text-25-344 bde-f-text ribz-eyebrow\">\nThree areas, three protocols\n<\/p><h2 class=\"bde-f-text-25-345 bde-f-text ribz-h2\" id=\"pc-aree-title\">\nOne protocol for each area\n<\/h2><p class=\"bde-f-text-25-346 bde-f-text ribz-lead\">\nThe pathway is divided into three protocols, each dedicated to an area that longevity research considers central. They take place one after the other, always in the same order.\n<\/p><\/div><div class=\"bde-f-container-25-366 bde-f-container ribz-grid-3 ribz-pc-areas\"><article class=\"bde-f-container-25-353 bde-f-container ribz-card ribz-pc-area\" id=\"act-ibz\"><div class=\"bde-f-container-25-349 bde-f-container ribz-pc-area-media ribz-pc-area-media--act\"><img decoding=\"async\" class=\"bde-f-image-25-348 bde-f-image ribz-pc-area-img\" src=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-768x1278.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires.png 972w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-180x300.png 180w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-615x1024.png 615w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-768x1278.png 768w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-923x1536.png 923w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/act-ibz-infiammazione-hires-7x12.png 7w\" sizes=\"auto, (max-width: 972px) 100vw, 972px\" width=\"768\" height=\"1278\"><\/div><p class=\"bde-f-text-25-350 bde-f-text ribz-pc-area-kicker\">\n<span class=\"ribz-dot ribz-dot--sm ribz-dot--act\"><\/span>01 \u00b7 Inflammation\n<\/p><h3 class=\"bde-f-text-25-351 bde-f-text ribz-h3 ribz-h3--lg\">\nACT-IBZ\n<\/h3><p class=\"bde-f-text-25-352 bde-f-text ribz-text\">\nThe first protocol is dedicated to the area of inflammation: the response with which the body defends itself and which, over time, can remain active at low intensity.\n<\/p><\/article><article class=\"bde-f-container-25-359 bde-f-container ribz-card ribz-pc-area\" id=\"co-ibz\"><div class=\"bde-f-container-25-355 bde-f-container ribz-pc-area-media ribz-pc-area-media--co\"><img decoding=\"async\" class=\"bde-f-image-25-354 bde-f-image ribz-pc-area-img\" src=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-768x472.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires.png 1600w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-300x184.png 300w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-1024x629.png 1024w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-768x472.png 768w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-1536x944.png 1536w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/co-ibz-perfusione-hires-18x12.png 18w\" sizes=\"auto, (max-width: 1600px) 100vw, 1600px\" width=\"768\" height=\"472\"><\/div><p class=\"bde-f-text-25-356 bde-f-text ribz-pc-area-kicker\">\n<span class=\"ribz-dot ribz-dot--sm ribz-dot--co\"><\/span>02 \u00b7 Microcirculation\n<\/p><h3 class=\"bde-f-text-25-357 bde-f-text ribz-h3 ribz-h3--lg\">\nCO-IBZ\n<\/h3><p class=\"bde-f-text-25-358 bde-f-text ribz-text\">\nThe second is dedicated to microcirculation: the network of small vessels that brings oxygen and nutrients to each tissue.\n<\/p><\/article><article class=\"bde-f-container-25-365 bde-f-container ribz-card ribz-pc-area\" id=\"mo-ibz\"><div class=\"bde-f-container-25-361 bde-f-container ribz-pc-area-media ribz-pc-area-media--mo\"><img decoding=\"async\" class=\"bde-f-image-25-360 bde-f-image ribz-pc-area-img\" src=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-768x1279.png\" alt=\"\" loading=\"lazy\" srcset=\"https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires.png 972w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-180x300.png 180w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-615x1024.png 615w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-768x1279.png 768w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-922x1536.png 922w, https:\/\/reaclongevity.com\/wp-content\/uploads\/2026\/10\/mo-ibz-metabolismo-hires-7x12.png 7w\" sizes=\"auto, (max-width: 972px) 100vw, 972px\" width=\"768\" height=\"1279\"><\/div><p class=\"bde-f-text-25-362 bde-f-text ribz-pc-area-kicker\">\n<span class=\"ribz-dot ribz-dot--sm ribz-dot--mo\"><\/span>03 \u00b7 Metabolism\n<\/p><h3 class=\"bde-f-text-25-363 bde-f-text ribz-h3 ribz-h3--lg\">\nMO-IBZ\n<\/h3><p class=\"bde-f-text-25-364 bde-f-text ribz-text\">\nThe third is dedicated to cellular metabolism, i.e. the way cells produce and use energy.\n<\/p><\/article><\/div><p class=\"bde-f-text-25-367 bde-f-text ribz-note\">\nThe names of the protocols indicate the area each one is dedicated to. The doctor assesses during the first visit whether the pathway is suitable for you. Images are for illustrative purposes only.\n<\/p><\/div><\/section><section class=\"bde-f-container-25-388 bde-f-container ribz-section\" aria-labelledby=\"pc-seq-title\"><div class=\"bde-f-container-25-387 bde-f-container ribz-wrap ribz-split ribz-split--center\"><div class=\"bde-f-container-25-373 bde-f-container\"><p class=\"bde-f-text-25-370 bde-f-text ribz-eyebrow\">\nThe sequence\n<\/p><h2 class=\"bde-f-text-25-371 bde-f-text ribz-h2\" id=\"pc-seq-title\">\nAlways in the same order\n<\/h2><p class=\"bde-f-text-25-372 bde-f-text ribz-lead\">\nThe three protocols take place one after the other: first ACT-IBZ, then CO-IBZ and finally MO-IBZ. This is the sequence with which the Inside Blue Zone pathway was defined and studied, and it is the same in all the Longevity Centers in the network.\n<\/p><\/div><ol class=\"bde-f-container-25-386 bde-f-container ribz-pc-seq\"><li class=\"bde-f-container-25-377 bde-f-container ribz-pc-seq-item ribz-pc-seq-item--act\"><span class=\"bde-f-text-25-374 bde-f-text ribz-pc-seq-num\">\n1\n<\/span><span class=\"bde-f-text-25-375 bde-f-text ribz-pc-seq-name\">\nACT-IBZ\n<\/span><span class=\"bde-f-text-25-376 bde-f-text ribz-pc-seq-area\">\nInflammation\n<\/span><\/li><li class=\"bde-f-container-25-381 bde-f-container ribz-pc-seq-item ribz-pc-seq-item--co\"><span class=\"bde-f-text-25-378 bde-f-text ribz-pc-seq-num\">\n2\n<\/span><span class=\"bde-f-text-25-379 bde-f-text ribz-pc-seq-name\">\nCO-IBZ\n<\/span><span class=\"bde-f-text-25-380 bde-f-text ribz-pc-seq-area\">\nMicrocirculation\n<\/span><\/li><li class=\"bde-f-container-25-385 bde-f-container ribz-pc-seq-item ribz-pc-seq-item--mo\"><span class=\"bde-f-text-25-382 bde-f-text ribz-pc-seq-num\">\n3\n<\/span><span class=\"bde-f-text-25-383 bde-f-text ribz-pc-seq-name\">\nMO-IBZ\n<\/span><span class=\"bde-f-text-25-384 bde-f-text ribz-pc-seq-area\">\nMetabolism\n<\/span><\/li><\/ol><\/div><\/section><section class=\"bde-f-container-25-413 bde-f-container ribz-section ribz-section--alt\" id=\"come-si-svolge\" aria-labelledby=\"pc-seduta-title\"><div class=\"bde-f-container-25-412 bde-f-container ribz-wrap ribz-split\"><div class=\"bde-f-container-25-392 bde-f-container\"><p class=\"bde-f-text-25-389 bde-f-text ribz-eyebrow\">\nIn practice\n<\/p><h2 class=\"bde-f-text-25-390 bde-f-text ribz-h2\" id=\"pc-seduta-title\">\nHow the pathway works\n<\/h2><p class=\"bde-f-text-25-391 bde-f-text ribz-lead\">\nYour doctor will explain every detail before you start. Here is a summary of what to expect.\n<\/p><\/div><dl class=\"bde-f-container-25-411 bde-f-container ribz-specs ribz-pc-specs\"><div class=\"bde-f-container-25-395 bde-f-container ribz-spec\"><dt class=\"bde-f-text-25-393 bde-f-text ribz-spec-term\">\nWhere\n<\/dt><dd class=\"bde-f-text-25-394 bde-f-text ribz-spec-def\">\nAt the Longevity Center you choose, in a calm setting.\n<\/dd><\/div><div class=\"bde-f-container-25-398 bde-f-container ribz-spec\"><dt class=\"bde-f-text-25-396 bde-f-text ribz-spec-term\">\nA session\n<\/dt><dd class=\"bde-f-text-25-397 bde-f-text ribz-spec-def\">\nIt lasts about half an hour and you do it lying down, at rest.\n<\/dd><\/div><div class=\"bde-f-container-25-401 bde-f-container ribz-spec\"><dt class=\"bde-f-text-25-399 bde-f-text ribz-spec-term\">\nHow many sessions\n<\/dt><dd class=\"bde-f-text-25-400 bde-f-text ribz-spec-def\">\nThe complete programme includes 27 sessions, 9 for each protocol.\n<\/dd><\/div><div class=\"bde-f-container-25-404 bde-f-container ribz-spec\"><dt class=\"bde-f-text-25-402 bde-f-text ribz-spec-term\">\nAt what pace\n<\/dt><dd class=\"bde-f-text-25-403 bde-f-text ribz-spec-def\">\nSessions can be concentrated into a few days or spread out over time: you agree the frequency and schedule with your doctor.\n<\/dd><\/div><div class=\"bde-f-container-25-407 bde-f-container ribz-spec\"><dt class=\"bde-f-text-25-405 bde-f-text ribz-spec-term\">\nPreparation\n<\/dt><dd class=\"bde-f-text-25-406 bde-f-text ribz-spec-def\">\nNo special preparation is needed.\n<\/dd><\/div><div class=\"bde-f-container-25-410 bde-f-container ribz-spec ribz-spec--last\"><dt class=\"bde-f-text-25-408 bde-f-text ribz-spec-term\">\nYour treatments\n<\/dt><dd class=\"bde-f-text-25-409 bde-f-text ribz-spec-def\">\nThe pathway does not replace your current treatments: the doctor takes them into account and, if necessary, consults your regular doctor.\n<\/dd><\/div><\/dl><\/div><\/section><section class=\"bde-f-container-25-423 bde-f-container ribz-section\" aria-labelledby=\"pc-tech-title\"><div class=\"bde-f-container-25-422 bde-f-container ribz-wrap ribz-split ribz-split--center\"><div class=\"bde-f-container-25-417 bde-f-container\"><p class=\"bde-f-text-25-414 bde-f-text ribz-eyebrow\">\nThe method\n<\/p><h2 class=\"bde-f-text-25-415 bde-f-text ribz-h2\" id=\"pc-tech-title\">\nREAC Technology\n<\/h2><p class=\"bde-f-text-25-416 bde-f-text ribz-lead\">\nThe sessions use REAC Technology, developed and studied by the Istituto Rinaldi Fontani in Florence for over thirty years. The pathway does not involve medication, supplements or other substances.\n<\/p><\/div><div class=\"bde-f-container-25-421 bde-f-container ribz-card ribz-card--surface ribz-pc-pro\"><p class=\"bde-f-text-25-418 bde-f-text ribz-kicker\">\nFor doctors and healthcare professionals\n<\/p><p class=\"bde-f-text-25-419 bde-f-text ribz-text\">\nTechnical and scientific information on technology, protocols and documentation is reserved for professionals and can be found on REAC Professionals.\n<\/p><a class=\"bde-f-text-link-25-420 bde-f-text-link ribz-link\" href=\"https:\/\/professionals.reaclongevity.com\/\" target=\"_blank\" rel=\"noopener\">\nGo to REAC Professionals \u2197\n<\/a><\/div><\/div><\/section><section class=\"bde-f-container-25-432 bde-f-container ribz-section ribz-section--dark\" aria-labelledby=\"pc-cta-title\"><div class=\"bde-f-container-25-431 bde-f-container ribz-wrap ribz-wrap--band\"><div class=\"bde-f-container-25-430 bde-f-container ribz-cta-band\"><div class=\"bde-f-container-25-426 bde-f-container ribz-cta-copy\"><h2 class=\"bde-f-text-25-424 bde-f-text ribz-h2 ribz-h2--light ribz-h2--sm\" id=\"pc-cta-title\">\nIt all starts with a visit\n<\/h2><p class=\"bde-f-text-25-425 bde-f-text ribz-text ribz-text--light\">\nThe doctor listens to your story and assesses with you whether the Inside Blue Zone pathway is suitable for you.\n<\/p><\/div><div class=\"bde-f-container-25-429 bde-f-container ribz-actions\"><a class=\"bde-f-text-link-25-427 bde-f-text-link ribz-btn ribz-btn--aqua\" href=\"https:\/\/reaclongevity.com\/en\/longevity-center\/#trova-centro\" target=\"_self\">\nFind a centre \u2192\n<\/a><a class=\"bde-f-text-link-25-428 bde-f-text-link ribz-btn ribz-btn--line\" href=\"https:\/\/reaclongevity.com\/en\/domande-frequenti\/\" target=\"_self\">\nFrequently Asked Questions\n<\/a><\/div><\/div><\/div><\/section><\/main>","protected":false},"excerpt":{"rendered":"<p>The Inside Blue Zone Path A Path to Care for Your Longevity Three Areas, a Defined Sequence, and a Doctor Following You From Beginning to End: Here's How the Path You Can Start in a Network Longevity Center Works. Find a center \u2192 How a session takes place Three areas, three protocols A [...]<\/p>","protected":false},"author":1,"featured_media":1268,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_breakdance_hide_in_design_set":false,"_breakdance_tags":"","footnotes":""},"class_list":["post-25","page","type-page","status-publish","has-post-thumbnail","hentry"],"_links":{"self":[{"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/pages\/25","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/comments?post=25"}],"version-history":[{"count":4,"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/pages\/25\/revisions"}],"predecessor-version":[{"id":1572,"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/pages\/25\/revisions\/1572"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/media\/1268"}],"wp:attachment":[{"href":"https:\/\/reaclongevity.com\/en\/wp-json\/wp\/v2\/media?parent=25"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}