reac longevity blog

Chronic silent inflammation: what it is and why it accelerates ageing

Chronic silent inflammation is one of the main factors in ageing. Find out what it is, what it depends on and why it is so relevant to health.

  • 15 May 2026
  • Prof. Dott. Salvatore Rinaldi
inflammation-chronic-silent-and-aging-reac

Inflammation is a key process for survival. However, when it remains active over time at low intensity, it can turn into a biological deterioration factor.. This condition is called chronic silent inflammation..

Unlike acute inflammation, it does not produce obvious symptoms. It does not cause immediate pain or easily recognizable clinical signs, but acts progressively and continuously. Numerous evidence indicates that this condition is involved in the main processes associated with ageing, contributing to reduced cell efficiency and loss of adaptive capacity..

The causes are multifactorial: prolonged stress, unbalanced diet, sedentary lifestyle and environmental factors. For this reason, the research is moving towards strategies capable of intervening upstream of inflammatory processes, favoring the rebalancing of biological regulation mechanisms.

Understanding and addressing chronic silent inflammation means taking action on one of the main drivers of ageing. In this scenario, we insert clinical approaches developed to intervene on biological regulation mechanisms, such as the project REAC Inside Blue Zone™, which translates this knowledge into structured protocols aimed at rebalancing inflammatory processes.

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